Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcb146c68b67089013b4c7a614504254 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y113-12005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y308-01005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y10-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y10-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_948b293bc7c389484cfdc63d3578f7c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04aff28afd316dbb438d9549f77a131a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e297326cd14dcb511f6f5b4ea3b39c75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_463c34ea78befc4deb790cec3eec5472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1b23e5b280aa86bf4673a28a7c77141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abdbdbc856bfd7e2894a4fe3d5acbc03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_604c15333bbb73434a68da252c7ac20a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed04378e2879e62198365d82fb2f5f1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81ab81405d3f0856a0cb250e3be42389 |
publicationDate |
2019-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019085305-A1 |
titleOfInvention |
Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
abstract |
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021119537-A1 |
priorityDate |
2003-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |