Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a60649a09a47690f2c5082c03fbc2212 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 |
filingDate |
2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_541ec8899d1442d8647a032cb9f0454d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35cbc634e29051a96f65c7c940ca5549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_201680bf0adba74f18de39e456360e43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_892364e46db92d67cbe37bf9470d5c72 |
publicationDate |
2019-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019085096-A1 |
titleOfInvention |
Anti-vwf d'd3 single-domain antibodies and polypeptides comprising thereof |
abstract |
The invention relates to isolated single-domain antibodies (sdAb) directed against von Willebrand Factor (VWF) D′D3 domain and chimeric polypeptides comprising thereof such as blood clotting factors and their uses in therapy such as in the prevention and treatment of hemostatic disorders. The invention also rotates to a method of extending or increasing half-life of a therapeutic polypeptide comprising a step of adding to the polypeptide sequence of said therapeutic polypeptide at least one sdAb directed against VWF D′D3 domain. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11192937-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11192938-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11644471-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10858418-B2 |
priorityDate |
2016-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |