http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019085053-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_662dae74c0265b130755da02213700a7 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-785 |
filingDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e40bb75542c4c6a6052ba37e59887f18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19fdf2b8c107ba0f3769586c86bb2e3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_685c50763b833d185a432a1e5e82954c |
publicationDate | 2019-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2019085053-A1 |
titleOfInvention | Synthetic lung surfactant with enhanced stability and effectiveness |
abstract | Peptides suitable for preparation of lung surfactants are described. Examples include one that include a first fragment comprising the amino acid sequence of XWLXRALIKRIQAZI (SEQ ID NO: 1) or a first amino acid sequence having at least 90% sequence identity to SEQ ID NO: 1 and a second fragment comprising the amino acid sequence of RZLPQLVXRLVLRXS (SEQ ID NO: 2) or a second amino acid sequence having at least 90% sequence identity to SEQ ID NO: 2, wherein X is any amino acid but at least one amino acid at the X positions is not cysteine, or Z is any amino acid but at least one amino acid at the Z positions is not methionine. Surfactants that contain such peptides, and related compositions, methods of preparing and using the compositions are also described. |
priorityDate | 2015-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 160.