Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7a8bc5579e827d17e0fea66946640e6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0504 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-306 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0529 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-36082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0504 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-36 |
filingDate |
2016-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edb341b18520ce1663d2148017d7d68e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7768437444af040d0778a69195dda13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83f7775048243bea71bdc225200995d2 |
publicationDate |
2019-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019076653-A1 |
titleOfInvention |
Electrical substance clearance from the brain |
abstract |
A method is provided that includes implanting (a) a parenchymal electrode in or in contact with an outer surface of brain parenchyma of a subject identified as at risk of or suffering from a disease, and (b) a cerebrospinal fluid (CSF) electrode in a CSF-filled space of a brain of the subject, the CSF-filled space selected from the group consisting of: a ventricular system and a subarachnoid space. A midplane treatment electrode is disposed in or over a superior sagittal sinus. Control circuitry is activated to drive the parenchymal electrode and the CSF electrode to drive a substance from the brain parenchyma into the CSF-filled space of the brain, and apply a treatment current between the CSF electrode and the midplane treatment electrode to drive the substance from the CSF-filled space of the brain to the superior sagittal sinus. Other embodiments are also described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4031235-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021251882-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-2030191-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11413455-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11141588-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-543899-C2 |
priorityDate |
2015-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |