Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b7274a7a3c27f72f1d430c8ab34ef69 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-282 |
filingDate |
2018-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54bda5cc0ffa2a9d55a23411f81021e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d311b5f32b361fdf713cbb1df967ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3164f441cf65b04daf5b5fa047adb417 |
publicationDate |
2019-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019076391-A1 |
titleOfInvention |
Methods of Subtyping CRC and their association with Treatment of Colon Cancer Patients With Oxaliplatin |
abstract |
A gene expression signature identifies stage II colon and/or Stage III cancer patients who will receive benefit from oxaliplatin. Oxaliplatin has been shown to lengthen the survival of colon cancer patients, when it is combined with 5-fluorouracil plus leucovorin (FULV) in NSABP clinical trial C-07. Gene expression signatures are used first to classify tumors with regard to their respective subtypes, enterocyte, TA, goblet, inflammatory and stem-like and detection of expression of the enterocyte subtype directs treatment of the patient with oxaliplatin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022182661-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022240158-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112725443-A |
priorityDate |
2014-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |