| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 |
| filingDate |
2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74d8e4156aed38897067a6deb0adfe8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3834c7fa7ba6c9278793987c4d63057f |
| publicationDate |
2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019062709-A1 |
| titleOfInvention |
Methods and compositions for maintenance of hematopoietic stem cells with preservation of self-renewal capacity |
| abstract |
Disclosed herein are methods of culturing hematopoietic stem cells (HSCs) that enhance preservation of the HSCs self-renewal capacity and multipotency for extended periods of time. Specific embodiments comprise culturing methods that involve use of a unique low calcium media. Certain embodiments comprise methods that enable the maintenance of multipotent and self-renewing HSCs for over two weeks. Certain embodiments avoid the use of chemicals that have the risk of unexpected off-target effects or mutagenicity. |
| priorityDate |
2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |