abstract |
Compounds having a structure according to formula (I), (II), or (III) n n n n n n n n n n where R 1 , R 2 , R 3 , R 5 X 1 , X 2 , and X 3 are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action. |