Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0eedf57f4a4e487d7872cb14f7b3c925 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-20 |
filingDate |
2016-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cb92e9d61de910abab0f1c598f15891 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65272ca8fa22977c5cc8bdff8de848c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c9349f26032801e47a8b4fbb1211d1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0296cffcdff0cde5139a83fb047b42d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41f89a7d40d655e1451ac5709b93384d |
publicationDate |
2019-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019025303-A1 |
titleOfInvention |
Borrelia immunoassays and materials therefor |
abstract |
The present invention relates to an immunoassay for the detection of Borrelia specific IgG, IgM and IgG/IgM antibodies in biological samples suspected of Lyme infection. The immunoassay can be performed via a standard immunoassay format or on an automated platform. In various embodiments, the immunoassay uses one or more Borrelia specific chimeric peptides VlsE-FlaB (designated pFlaB-mV), VlsE-ErpP (designated pErp59-mV), VlsE-P35 (designated pP35-mV) alone or in combination with one or more outer surface protein C (Osp C) types B or I, p58 and DbpA. Other aspects of the invention provide antigen/substrate combinations and compositions comprising combinations of the disclosed peptides and/or proteins for use in the immunoassays described herein. |
priorityDate |
2015-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |