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filingDate 2017-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57aff4acb84ad0a45faba1e66009c74a
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publicationDate 2019-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2019024261-A1
titleOfInvention Compartmentalised combinatorial chemistry by microfluidic control
abstract The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalizing two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reaction between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control. The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalized into the microcapsules.
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