Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_849b873488ec2cdb529cf36a6ecee3a8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
filingDate |
2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fc076ac306862a11cbd6b13597bb097 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f29ee6f7cd51256e1e5471e3ca15bef7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69ef150446363c27e2c96b81f14a031b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_358c24611270d1ae8f2f33bd916f0eae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_630b2b4b748295e2fdaa9941906fb179 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64bb54b06df74b7fdc7cd974e75ba3cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_518343c0fe10acf8a1a47a61dfa2d8ce |
publicationDate |
2019-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019016703-A1 |
titleOfInvention |
Bifunctional compounds for her3 degradation and methods of use |
abstract |
The present invention provides bifunctional compounds which act as protein degradation inducing moieties for a HER family protein, such as Her3. The present invention also provides methods for the targeted degradation of a HER family protein through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to the HER family protein which can be utilized in the treatment of disorders modulated by a HER family protein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10450310-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10532103-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022261627-A1 |
priorityDate |
2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |