| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22b9baa71ceef111b94d9fcf4391f1f0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0474
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J41-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1282
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0478
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J41-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-36 |
| filingDate |
2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3131fc3d5b6c4cacd3a4d2a9f90a9cce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_125f4ee726e5671711787c96159bdbf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e1e6718ae81350ed6f3d9b356a4e8e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da8394359e0d77474fadf765eea4bd0c |
| publicationDate |
2019-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019015530-A1 |
| titleOfInvention |
Isotope preparation method |
| abstract |
The present invention provides a method for the purification of 227Th from a mixture comprising 227Th and 223Ra, said method comprising: i) preparing a first solution comprising a mixture of 227Th and 223Ra ions dissolved in an aqueous solution of first mineral acid; ii) loading said first solution onto a strong base anion exchange resin; iii) eluting 223Ra from said strong base anion exchange resin using a second mineral acid in an aqueous solution; iv) optionally rinsing said strong base anion exchange resin using a first aqueous medium; v) eluting 227Th from said strong base anion exchange resin using a third mineral acid in an aqueous solution whereby to generate a second solution comprising 227Th. The invention further provides a purified 227Th solution, a corresponding pharmaceutical formulation and methods of treatment of neoplastic disease. |
| priorityDate |
2016-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |