Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1542e8802a0e6a7a8a7c6bd5627eb857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e340f2d33a029cc1a8fb5e0b5ed04318 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 |
filingDate |
2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_170e57f946b3fefcaeca7a34e6173e92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_025d3d5a05d534630594b074b80ef9c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0192391486d84ce27c0f4d8a43fdf34f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f7812e3de8f3888cc4ba01e9b0571e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aec89a12491f3e10be93000e091edcff |
publicationDate |
2019-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019002977-A1 |
titleOfInvention |
Growth Differentiation Factor 15 as Biomarker for Metformin |
abstract |
The present invention relates to metformin for use in treating a patient, wherein the patient exhibits an increased level of GDF15 in response to metformin treatment; to methods of identifying a patient who will benefit or who will not benefit from metformin treatment; methods of treating a patient at risk of developing or suffering from a disease or disorder comprising administering therapeutically effective amount of metformin; methods of adapting the dosage of metformin; the usage of GDF15 as biomarker for identifying a patient who will benefit or who will not benefit from metformin treatment, kits for use in identifying a patient who will benefit from metformin treatment and the use of the kits, as well as methods of treating a patient or who will not benefit from metformin treatment. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113893349-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113238060-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111281867-A |
priorityDate |
2015-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |