http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018373832-A1

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filingDate 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2394c774eac2df6b64a8a1f8b0597def
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publicationDate 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2018373832-A1
titleOfInvention Detecting cross-contamination in sequencing data
abstract Detecting cross-contamination between test samples used for determining cancer in a subject is beneficial. To detect cross-contamination, test sequences including at least one single nucleotide polymorphism are prepared using genome sequencing techniques. Some of the test sequences can be filtered to improve accuracy and precision. A prior contamination probability for each test sequence is determined based on a minor allele frequency. A contamination model including a likelihood test is applied to a test sequence. The likelihood test obtains a current contamination probability representing the likelihood that the test sample is contaminated. The contamination model can also determine a likelihood that the sample includes loss of heterozygosity representing the likelihood that the test sequence is contaminated. Test samples that are contaminated are removed. A source for the contaminated test sample can be found by comparing contaminated test sequences to other test sequences.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115083529-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11462300-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021173885-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022072537-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109886342-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022061189-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023015244-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022056296-A1
priorityDate 2017-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 41.