http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018363020-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b87b47407d929b7852321461253c5fa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-35 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 |
| filingDate | 2018-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_982e5ad3d52a24f64198594fb1a63bab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33fd60fa2c1d57baa3b1310dec0f22d9 |
| publicationDate | 2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2018363020-A1 |
| titleOfInvention | Pathogen detection method |
| abstract | The present invention provides a method of detecting a Mycobacterium-specific metabolite in the form of mycothiol in a biological sample in vitro, including the steps of preparing a reaction mixture by combining the biological sample with an enzymatic solution containing a reaction buffer, nicotinamide adenine dinucleotide (NAD) and a formaldehyde dependent mycothiol dehydrogenase (FD-MDH); allowing reduction of NAD in the reaction mixture by interaction of FD-MDH with a predetermined Mycobacterium-specific metabolite in the form of mycothiol if present in the biological sample; and detecting reduced NAD within the sample, indicative of the presence of mycothiol in the biological sample and thus of a Mycobacterium infection in the source of the biological sample. |
| priorityDate | 2017-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.