Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5154 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001106 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2016-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1357e47cb96fd81bcae59f6a276664d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07f0134bed0c0b6b880caf7de231ce5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d5bf6e85583eb20b32aead1a032d340 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ec527b2d854ea83a4a236b22eb8f580 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e783071f04967d108a13725092bc6c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01964ec91ab8fb6000714993d4c0207d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa57c9f06c7885fd1f8483c1e377922d |
publicationDate |
2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018344828-A1 |
titleOfInvention |
Compositions and methods for the treatment of her2-expressing solid tumors |
abstract |
Recombinant adenoviruses expressing the extracellular (EC) and transmembrane (TM) domains of human HER2 (HER2ECTM) are described. The recombinant adenoviruses express a chimeric fiber protein having the adenovirus type 35 (Ad5) shaft and knob domains, which facilitates transduction of human dendritic cells by the recombinant HER2ECTM expressing adenovirus. Compositions that include dendritic cells transduced by the recombinant adenovirus and their use for treating HER-positive tumors is described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022216831-A1 |
priorityDate |
2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |