abstract |
A method of treating cosmetic skin conditions in an individual comprising the steps of preparing a composition comprising an all-D amino acid peptide and a pharmaceutically acceptable carrier. The D peptide has the general structure: A-B-C-D-E in which: A is Ser, Thr, Asn, Glu, Arg, Ile, B is Ser, Thr, Asp, Asn, C is Thr, Ser, Asn, Arg, Trp, D is Tyr, and E is Thr, Ser, Arg, or Gly and wherein all amino acids in the D peptide are the D stereoisomeric configuration and said peptide composition is administered in a cosmetically effective dose wherein said composition acts to improve the appearance of the skin. The D peptide may have a terminal amide (—NH 2 ) or methyl ester moiety to enhance its activity and penetration into the skin. |