http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018327829-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b57bb783f190adb19b06524573447e9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
| filingDate | 2018-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c36371abce7db1bf822bb89e9d52cfcd |
| publicationDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2018327829-A1 |
| titleOfInvention | Super-Resolution Sequencing |
| abstract | A method for template-directed sequencing-by-synthesis of an array of target polynucleotide can include:n (a) providing an array of target polynucleotides in a fluidic vessel; (b) contacting the array of polynucleotides with a solution comprising (i) polymerization complex and (ii) reversibly terminating and differently labeled A,C,G, and T/U nucleotides; (c) incorporating one of the differently labeled nucleotides, using the polymerization complex, into a chain complementary to at least one of the array of polynucleotides; (d) binding imaging tags to the differently labeled nucleotides of step (c); (e) imaging and storing the identity and position of the imaging tags of step (d); (f) reversing termination (b)-(e); (g) repeating steps (b)-(e) and assembling a sequence for each of the array of target polynucleotides from the stored identity and position of the imaging tags, optionally as a homogeneous or one pot reaction. Additional methods of sequencing target polynucleotides are described herein. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112746094-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11427867-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020370113-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11590505-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022057584-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020112964-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10982260-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020243187-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022232709-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11761040-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113795595-A |
| priorityDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 794.