| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c00305de01111733a9d129288f2172ac |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate |
2016-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_587d0c2d275837b355ca915b9c3a67cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_602d4df9664812cca118396b7d5260c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60245569380ca6e9891254e561a0aed3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bcf3c60718396df1308d1652c7c8fce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a94584b4194b69b52bfc2eb37685d138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c8d87e67b45e37988397b6f3a365112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95d082d6e18a697bdd1d4a02f395ef55 |
| publicationDate |
2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018327386-A1 |
| titleOfInvention |
Crystalline forms of (r)-n-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1h-indole-3-carboxamide |
| abstract |
The present disclosure relates to a crystalline Forms A, B, and C of (R)—N-((4-methoxy-6-methyl-2-oxo-1,2-di-hydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide, each of which are useful as modulators the activity of histone methyl modifying enzymes. The present disclosure also provides pharmaceutically acceptable compositions comprising the crystalline forms and methods of using said compositions in the treatment of various disorders. |
| priorityDate |
2015-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |