Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58f64475f34f9a62e4e264160414b6ae |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_963e49cdcc1f6e20130b56e59b052e95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f3fcc7b6945ddf3ce2fdafdc0081d83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ddfda2cf0ff00f85eb793d7a54b3490 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66e12780c138e9c5aa3fb8d0149fc759 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aac23dd6ae9792f2195c7d4f75ecb582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d5288730f3e8c5cc6cb58ac20e5af59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41c2e4a6e0bbc57f1ad137543d34cf04 |
publicationDate |
2018-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018297995-A1 |
titleOfInvention |
Pyrimidine or pyridopyridone compound and application thereof |
abstract |
The present invention discloses a pyrimidine or pyridopyridone compound as shown in formula (I) and an application thereof relating to the technical field of medicament preparation. The compound can selectively suppress cyclin-dependent kinases (Cdks) CDK4 and CDK6 with almost no suppression of the activity of the kinase CDK2. Thus, the compound can be used for various diseases caused by cell cycle control disorders involving CDK4 and CDK6, and particularly in the treatment of malignant tumors. |
priorityDate |
2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |