Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc5005f9c9a6b5824bffaf2e89165648 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-035 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2018-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9638ab4363893998c859a8e309ebef9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f81f4d0919ce85a63a2b5b1af4868ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e638bea982e6f2e54e95ba7c8076c45b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ba4873aaeda04cfa1b42ba70db845bf |
publicationDate |
2018-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018288985-A1 |
titleOfInvention |
Poly-glutamine androgen receptor knock-in mouse models, reagents and methods |
abstract |
A knock-in non-human mammal comprising a recombinant androgen receptor (AR) cassette containing an exogenous human polyglutamine (polyQ) tract encoding sequence in exon 1, wherein the human polyQ tract encoding sequence is stably integrated into the genome of the animal. Also provided are recombinant cells, fertilized eggs and tissues. The resulting animal displays a wide range of phenotypes, best characterized as Metabolic Syndrome and can be used in screening and other assays. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114586735-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114731985-A |
priorityDate |
2017-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |