| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efb35e154fff5d3177ae8520d41046d5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-161
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6837
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate |
2018-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98b68e5fc75f61832b946b949f8e4812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4aa434a6f6d3a1bf5eceac1d30f50592
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d56403486bc0475281d69aaec0b7414
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2512295a98b2c9746efdbd5d59a159f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b1cd09c31376db629941e72945bb45f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe6b2c89d832dad0e8ac014ac720c27e |
| publicationDate |
2018-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018251862-A1 |
| titleOfInvention |
Capture Probes Immobilizable Via L-Nucleotide Tail |
| abstract |
The invention provides chimeric capture probes immobilizable via an L-nucleic acid tail that can bind to a complementary L-nucleic acid in an immobilized probe. The capture probes are useful for capturing a target nucleic acid from a sample. The L-nucleic acid in the tail of the capture probe bind to the complementary L-nucleic acid in the immobilized probe with similar affinity as would otherwise equivalent D-nucleic acids. However, the L-nucleic acid of the capture probe tail and immobilized probes do not form stable duplexes with D-nucleic acids present in the in the sample containing the target nucleic acid. Binding of nucleic acids in the sample directly to immobilized probe or to the tail of the capture probe is reduced or eliminated increasing the sensitivity and/or specificity of the assay. |
| priorityDate |
2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |