Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-545 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
filingDate |
2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01a9ca3d93c25f9879887c153830efc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0753db4ee387553bbed90f8a06b745db |
publicationDate |
2018-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018250335-A1 |
titleOfInvention |
Modified cells evoking reduced immunogenic responses |
abstract |
Embodiments of this disclosure relate to techniques and systems for preparing modified cells evoking reduced immunogenic responses and application thereof. For example, hypo-immunogenic (e.g., decreased immunogenicity) and compatible stem cells may be obtained by a disruption in Transporter associated with antigen presentation 1 (TAP1) or TAP-associated glycoprotein (TAPBP) genes while maintaining normal pluripotency, karyotypes, and differentiation ability of these cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111979243-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021251271-A1 |
priorityDate |
2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |