| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e8f93a1343a400a745b221c18d9af30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ae079092f2e6b17a5c5110af960b6c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a40ccc6fdf7585ed571dcf23653917ff |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2016-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97ecdbe854c126a12a98a12a340dfc3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c868c48c25ffba9f44adbbf244cbd84b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1fd212ca3399320110f02d1038e04b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a18635936dec8f69cc4b19fdb66b781a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6fe8b8d4bce612610eb0b97384b24ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_759113724bdfa3c7181cd49b0b3fb0da |
| publicationDate |
2018-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018246118-A1 |
| titleOfInvention |
Isotopic methods for measurement of tryptophan and metabolites thereof |
| abstract |
Tryptophan degradation is a key metabolic pathway controlling immune reactions and evidence suggests that during cancer progression generation of tryptophan metabolites may be fundamental for immune escape promoting the malignant phenotype of cancer cells in an autocrine fashion. The present invention relates to methods of measuring mass tag labelled tryptophan and metabolites thereof and methods using the labelled molecules for monitoring in a subject the effectiveness of a treatment and of disease recurrence after treatment, for stratifying patients and for diagnosing suppression of an immune response in a subject. |
| priorityDate |
2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |