| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1815a8481b7309f04fd263fa2b9498a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-149
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-1006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M47-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-1459
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
| filingDate |
2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a66f9b80e17431e8aaa32942a1efe4fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd38c163e3c00ac2ba6f164b472fdbda
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e7852800f96257c953b716693c08d27 |
| publicationDate |
2018-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018245051-A1 |
| titleOfInvention |
Methods for generating induced pluripotent stem cells via cell cycle synchronization |
| abstract |
The techniques described herein provide for improved efficiency of iPSC production from biological cells. The approach achieves improved iPSC production efficiency by obtaining a set of cells whose cell cycles are synchronized at a specific, desired cell cycle phase, such as mitotic phase (also referred to as M phase). The efficacy with which such synchronized cells can be transformed into iPSCs is higher than for an arbitrary set of cells that comprises cells at a variety of different stages in their cycles. Accordingly, the approaches described herein allow efficient generation of iPSCs, thereby facilitating myriad technologies for personalized and regenerative medicine that rely upon the effective production of iPSCs. |
| priorityDate |
2015-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |