| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f715ca5afc11b8290f8f916a3326606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcd5a951a8c4a137b6f0f0511324e019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66b6484e61b84976b4af5755a94cbf75 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-607
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-101 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
| filingDate |
2017-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79ef321e27a7adc09a6d02e22efb96a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc4292d1eb3126d16d1d2b2b8f56e3f6 |
| publicationDate |
2018-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018223351-A1 |
| titleOfInvention |
Nanopore Based Molecular Detection and Sequencing |
| abstract |
This disclosure provides systems and methods for molecular identification and polymer (e.g., nucleic acid) sequencing using nanopores. The polymer may be passed through or in proximity to the nanopore and various subunits of the polymer may affect the current flowing through the nanopore. The various subunits may be identified by measuring the current at a plurality of voltages applied across the nanopore and/or membrane. In some cases, the polymerization of tagged nucleotides presents tag molecules to the nanopore that can be identified by measuring the current at a plurality of voltages applied across the nanopore and/or membrane. Also provided herein are systems and methods for sequencing both the sense and anti-sense strand of a double stranded nucleic acid molecule with a nanopore and methods for using ribonucleic acid (RNA) speed bump molecules to slow the passage of a nucleic acid molecule through or in proximity to a nanopore. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913978-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021231920-A1 |
| priorityDate |
2012-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |