| abstract |
The invention relates to a preparation system for preparing a sample for electron microscopy, comprising:—a liquid handling system ( 0 ) comprising a dispensing head ( 1 ), wherein said liquid handling system ( 0 ) is configured to aspirate and dispense a volume of a sample via the dispensing head ( 1 ),—a support structure ( 2 ) that is configured to accommodate the sample, a temperature-controlled stage ( 4 ) that is configured to keep said support structure ( 2 ) at a pre-defined temperature when the support structure ( 2 ) is arranged on the temperature-controlled stage ( 4 ), a first adapter ( 3 ) configured to hold said support structure ( 2 ), a transfer mechanism ( 60 ) that is configured to be connected to the first adapter ( 3 ) holding the support structure ( 2 ) and to move said support structure ( 2 ) into a container ( 8 ) containing a liquid cryogen ( 80 ) so that the sample on the support structure ( 2 ) contacts the cryogen ( 80 ). Furthermore, the invention relates to a corresponding method. |