http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018187267-A1

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filingDate 2018-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bf4bdf3b0e4a0846d0b68f2717376f8
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publicationDate 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2018187267-A1
titleOfInvention Method for conducting early detection of colon cancer and/or of colon cancer precursor cells and for monitoring colon cancer recurrence
abstract The invention provides a kit for detecting the presence or absence of mutations in the selected regions of the target genes associated with colorectal cancer, comprising XNA clamps and primers; wherein the XNA clamps are capable of hybridizing with the selected regions having wild-type sequences in the target genes, and the primers are capable of amplifying the selected regions containing each of the mutations in the target genes. The invention also discloses a method of detecting a mutant gene associated with colorectal cancer, comprising: providing a sample containing DNA and a xeno nucleic acid clamp capable of hybridizing to a wild-type gene; and detecting a mutant of the gene in the sample with a xeno nucleic acid probe capable of hybridizing to the mutant gene.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022275450-A1
priorityDate 2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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