Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd698bacfaf52f81addc4a2bd0261a6e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-78 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-925 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
2016-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9559e76037adf64301aa1d7a305e7901 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da9516fec400c58b2578bd69295a0a6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcd6a6bbbc013490cc23541a850aeda1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_595eedf02e704daa27918f199bbeeb65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1250bcb12fdff410f1721a16b8f191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd12392d95c562473a5e0b41ed6d2278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c2bccd3d0414e5729a5745173aa3782 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7809949f176827eebef7a200f6745248 |
publicationDate |
2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018186848-A1 |
titleOfInvention |
Thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect and cosmetic composition for improving skin wrinkle and maintaining elasticity of skin comprising the same as effective component |
abstract |
A thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect has the amino acid sequence of SEQ ID NO: 2, a gene of E. coli codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the human epidermal growth factor-spider venom fusion protein, a recombinant vector including the gene, a host cell transformed with the recombinant vector, and a method for producing in a host cell a human epidermal growth factor-spider venom fusion protein by transforming a host cell with the recombinant vector, and a cosmetic composition for improving skin wrinkle and maintaining skin elasticity including a human epidermal growth factor-spider venom fusion protein, and as the cosmetic composition has excellent thermostability and has an effect of enhancing the activity of improving skin wrinkle and maintaining skin elasticity, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery. |
priorityDate |
2016-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |