| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fec576c38e34882531ca37d6b922bf42 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-313
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D327-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D327-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 |
| filingDate |
2016-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dc33e37ce8c7b0d5abd7542668d004f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1236992d73fc71503cc393b1f6b3382f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c968998443faab2e269da55567147c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76572bc2100ee5c047e61235865eb2ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd38a79fb61b4c8cbde6362cf4ae1e85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59e6a3bc070646e22ac3307357d9d3c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64fa33f25d6bfd5feaf095a9310320ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef83fb580791e38e956670c9fc650081 |
| publicationDate |
2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018186763-A1 |
| titleOfInvention |
Method for Producing Fluorine-Containing Cyclopropane Carboxylic Acid Compound |
| abstract |
The present invention provides an industrially applicable method for production of a fluorine-containing cyclopropane carboxylic acid compound useful as an intermediate for pharmaceutical and agrichemical products. A fluorine-containing cyclopropane monoester is obtained by: forming a fluorine-containing cyclic sulfate with the use of a fluorine-containing dial compound and sulfuryl fluoride (as a cyclic sulfuric esterification step); reacting the fluorine-containing cyclic sulfate with a malonic diester, thereby forming a fluorine-containing cyclopropane diester (as a cyclopropanation step); and hydrolyzing the fluorine-containing cyclopropane diester (as a hydrolysis step). The fluorine-containing cyclopropane carboxylic acid compound, such as fluorine-containing cyclopropane monoester or its salt, can be obtained with high chemical and optical purity by mixing the fluorine-containing cyclopropane monoester with an amine and subjecting the resulting salt of the fluorine-containing cyclopropane monoester and amine to recrystallization purification. |
| priorityDate |
2015-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |