| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b19a99258e59155c8ecc16cf42a46492
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20022ce830fd8e6a8e84696b805a14d3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-003 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate |
2017-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d60f00628c92d971bf1ef2600bece2b7 |
| publicationDate |
2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018179502-A1 |
| titleOfInvention |
Nucleic Acid Analogue-Guided Chemical Nuclease System, Methods and Compositions |
| abstract |
Nucleic acid analogue-guided chemical nuclease systems, methods and compositions, which can manipulate the genome DNA sequence in a sequence-specific manner. The core components that together make up the architecture of the system are: nucleic acid analogues (e.g. Peptide nucleic acids) and bleomycin or its derivatives. Generally speaking, these components are structured such that nucleic acid analogues which recognize specific DNA sequences are conjugated ( covalently) to bleomycin or its derivatives which can cleave the target DNA. This architecture allows the method to sequence-specifically insert or remove DNA sequence from the target DNAs. |
| priorityDate |
2016-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |