| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af92759c928daeb7f0daabbb0499f059 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-464 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 |
| filingDate |
2017-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c9c88b98cff557df6c88771f827b5f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46d279be1d3550ce0af8477fbf544a7c |
| publicationDate |
2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018179298-A1 |
| titleOfInvention |
Method for controlling affinity of antibody for antigen, antibody whose affinity for antigen has been altered, and its production method |
| abstract |
Disclosed is a method for controlling affinity of an antibody for an antigen, comprising substituting at least 3 amino acid residues of framework region 3 (FR3) defined by the Chothia method with charged amino acid residues, in an antibody whose electrical characteristic of complementarity determining region (CDR) based on the amino acid sequence of the CDR is neutral or negatively charged. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10995133-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113248601-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3854808-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3854811-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3854812-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021149427-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021149428-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3854809-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3766899-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4019540-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4151651-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4177269-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3854810-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3854807-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3945319-A1 |
| priorityDate |
2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |