Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-653 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-0221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-0622 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-0622 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B27-46 |
filingDate |
2017-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ee9df758d86164aa1a0f8d6a4571276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dde2936db02f200bf0f645239c4ac68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ee349d3a476c4a4cbfac9baf94c8bad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bc97f94fe295f96634045a2375bcf2e |
publicationDate |
2018-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018173004-A1 |
titleOfInvention |
Devices, apparatus and method for providing photostimulation and imaging of structures |
abstract |
According to exemplary embodiments of the present disclosure, it is possible to provide method, system, arrangement, computer-accessible medium and device to stimulate individual neurons in brain slices in any arbitrary spatio-temporal pattern, using two-photon uncaging of photo-sensitive compounds such as MNI-glutamate and/or RuBi-Glutamate with beam multiplexing. Such exemplary method and device can have single-cell and three-dimensional precision. For example, by sequentially stimulating up to a thousand potential presynaptic neurons, it is possible to generate detailed functional maps of inputs to a cell. In addition, it is possible to combine this exemplary approach with two-photon calcium imaging in an all-optical method to image and manipulate circuit activity. Further exemplary embodiments of the present disclosure can include a light-weight, compact portable device providing for uses in a wide variety of applications. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11609414-B2 |
priorityDate |
2008-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |