Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-277 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2017-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f94caa848acbd15444bd01595dd3138b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ae078a2e300adca7e489475b19af605 |
publicationDate |
2018-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018153850-A1 |
titleOfInvention |
Compositions and methods for treatment of cancer |
abstract |
Methods and compositions are provided for treatment of cancer, including prostate cancer. In one aspect, the present invention provides a composition comprising a taxane and a drug that reduces efflux of the taxane from a cell. The drug that reduces efflux of the taxane can be an inhibitor of ABCB1 efflux activity. In some cases, the inhibitor of ABCB1 efflux activity is an inhibitor of ABCB1 ATPase activity selected from the group consisting of enzalutamide and bicalutamide. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11215617-B2 |
priorityDate |
2015-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |