| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_751430a32763964dbc7195a2d58cffbc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-302
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2814
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2828
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate |
2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2cc3dc50689d50429796a3a35de2ee1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf15d889f36cd1d2df2130b8543c3e28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c98999d7c8789c53a0a73aca92959ba |
| publicationDate |
2018-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018134775-A1 |
| titleOfInvention |
Alpha-Synuclein Antibodies (7A11) |
| abstract |
The invention relates to an antibody or fragment thereof and the use of the antibody in a method of treatment and/or diagnosis. The antibody or fragment thereof specifically binds to alpha-synuclein, including monomeric, oligomeric and fibril forms of alpha-synuclein; is not cross reactive with beta-synuclein or gamma-synuclein; specifically binds human, rat and mouse alpha-synuclein; binds nitrated, oxidized and phosphorylated forms of alpha-synuclein; and binds an epitope of human alpha synuclein comprising the sequence MPSEEGYQDYEPEA (SEQ ID NO:2). The method for diagnosing a neurodegenerative disease associated with alpha-synuclein or for detecting alpha-synuclein, comprises adding the antibody or fragment thereof to a biological sample from a subject, and detecting the presence or absence of a complex formed between alpha-synuclein and the antibody or fragment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022024693-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11142570-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11292831-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261242-B2 |
| priorityDate |
2016-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |