| abstract |
A method for tumor marker detection is disclosed. The method includes preparing a biosensor, forming a reference solution by adding the biosensor to a buffer solution, measuring a first fluorescence intensity of the reference solution, forming a mixture by adding a suspicious biological solution to the reference solution, measuring a second fluorescence intensity of the mixture, and detecting a presence of a tumor marker responsive to a difference between the first fluorescence intensity and the second fluorescence intensity. The biosensor preparation includes forming a functionalized nanomotor by functionalizing a nanomotor with an aptamer, forming a blocked functionalized nanomotor by blocking gaps between functionalized parts of the functionalized nanomotor with a blocking agent, and attaching a fluorescence probe to the blocked functionalized nanomotor. |