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publicationDate 2018-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2018080008-A1
titleOfInvention Car-t lymphocytes engineered to home to lymph node b cell zone, skin, or gastrointestinal tract
abstract In one embodiment, provided herein are cells, e.g., T cells expressing receptors that that cause a cell expressing the receptors to home to specific anatomical regions, e.g., the B cell zone of lymph nodes, the gastrointestinal tract, or the skin. Also provided herein is use of such cells, e.g., T lymphocytes, to treat diseases such as cancer.
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