http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018066070-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4afb8b01aa8de7e0b24a86713b23a18 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_064eb285c0528c4b2ee40448ec5d02d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41e30a51b256c31e8dc23e542f264e43 |
publicationDate | 2018-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2018066070-A1 |
titleOfInvention | Acetylated pcsk9 |
abstract | The invention relates to antibodies reactive to acetylated PCSK9, particularly to PCSK9 acetylated in position Lys421, Lys273, Lys69, Lys83, Lys243, Lys258, Lys494, and/or Lys506, and related reagents. The invention also relates to a method of reducing LDL-cholesterol level in a patient in need thereof, said method comprising administering to the subject an effective amount of an antibody binding to acetylated PCSK9. The invention also relates to a method of treating a cholesterol related disorder in a patient in need thereof, said method comprising administering to the subject an effective amount of an antibody binding to acetylated PCSK9. The invention also relates to a method of treating hypercholesterolemia in a patient in need thereof, said method comprising administering to the subject an effective amount of an antibody binding to acetylated PCSK9. |
priorityDate | 2015-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 278.