Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c98f926132ddae7e51d5a75caeddf129 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b449a8a39562c78bc41956aa5454d918 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2016-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49fec11404290792ae83dc104e35d6d4 |
publicationDate |
2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018057564-A1 |
titleOfInvention |
Antagonists of il-20 family of cytokines and their use |
abstract |
Methods for blocking the activity of the IL-20 family of cytokines in a mammal having a disorder-mediated by one or more of the IL-20 family of cytokines consisting of IL-19, IL-20 and IL-24 are disclosed. The methods involve administering a therapeutically effective amount of either a soluble IL-20R2-IgG Fc fusion protein or a neutralizing monoclonal antibody to IL-20R2, both of which are able to block the biological functions of all three members of IL-20 family of cytokines. |
priorityDate |
2016-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |