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filingDate 2016-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2018057564-A1
titleOfInvention Antagonists of il-20 family of cytokines and their use
abstract Methods for blocking the activity of the IL-20 family of cytokines in a mammal having a disorder-mediated by one or more of the IL-20 family of cytokines consisting of IL-19, IL-20 and IL-24 are disclosed. The methods involve administering a therapeutically effective amount of either a soluble IL-20R2-IgG Fc fusion protein or a neutralizing monoclonal antibody to IL-20R2, both of which are able to block the biological functions of all three members of IL-20 family of cytokines.
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