Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e43b4ca6b41ce9f54c9a895d474c81a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2650-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2650-50 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-33324 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4748 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 |
filingDate |
2016-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba7f139a5a3fcf127b45bbe7b450cfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b6836d749bd9210ad42c35713390255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66cde81b04e920db8ade502cc036e2cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7041a23167ea042b69e5bae20242d7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89d9c0ef0544e43798119c01c1b537e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c947b365ed5cebc31eac746c74c463be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2f4451f90829a6245ad5a72408f409a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2b8fc8f207cccafb2a339407acda476 |
publicationDate |
2018-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018050112-A1 |
titleOfInvention |
Block Copolymer Conjugate Of Physiologically Active Substance |
abstract |
A physiologically active substance-conjugated block copolymer having enhanced efficacy and/or safety is provided by enhancing the property of penetrating into a target diseased tissue and/or enhancing excretability, compared to known physiologically active substance-conjugated block copolymer, and suppressing sensitization of the physiologically active substance to normal tissues other than a target diseased tissue. Disclosed is a block copolymer including a polyethylene glycol segment connected with a polyamino acid derivative segment conjugated with a physiologically active substance, in which the molecular weight of the block copolymer is from 2 kilodaltons to 15 kilodaltons, and the light scattering intensity of a 1 mg/mL aqueous solution of the physiologically active substance-conjugated block copolymer as measured with a laser light scattering photometer is at least twice or more the light scattering intensity of toluene. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10945997-B2 |
priorityDate |
2015-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |