| abstract |
Benzodiazepine dimers having a structure represented by n n n n n n n n n n wherein X comprises a heteroaromatic moiety and is as further defined in the application; R 1 is n n n n n n n n n n and the other variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC). |