Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f6df56a4e9b17d56d9c57dcf04c46b3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45eaf0a6f55cda423420fd7a872f7ff2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84961011dbf00c2a42d85127f09a3e82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e90eb8929b847e0025c99f99b19ede2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e616fd349310da9dee345f1ca500525d |
publicationDate |
2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018023145-A1 |
titleOfInvention |
Nucleic acid detection combining amplification with fragmentation |
abstract |
Provided herein are methods and compositions for detection of a nucleic acid target in a sample. The methods and compositions use primer directed amplification in conjunction with nucleic acid fragmentation. The methods have high sensitivity even in the presence of a large amount of non-target nucleic acid. Also provided are oligonucleotides and kits useful in the method. Exemplary nucleic acid targets are those with mutant gene sequence such as mutant sequence of the EGFR, APC, TMPRSS2, ERG and ETV1 genes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111748620-A |
priorityDate |
2007-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |