| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cbdadc877a0de10b24a69c1ab582ceb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-101
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-607
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-107 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2017-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bec345f3181345761715f8b827bcbf2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a39d3a81a346e50f24f672bb909b2c88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f6fd876b5226d5a8a08eb4c0540c815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1700211d53b61000e0ab93416e59127b |
| publicationDate |
2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018023129-A1 |
| titleOfInvention |
Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays |
| abstract |
The present disclosure provides methods and devices for simultaneous identification of a plurality of target nucleic acid sequences in a single sample chamber that includes an addressable array of nucleic acid probes attached to a solid surface. Addressable signals can be generated and measured, in real-time, upon hybridization of target sequences at the individual probe locations within the array while the temperature of the system is varied. Such generated signals, as a function temperature, can then be used to compute the properties of nucleic acid hybridization at each addressable location which is ultimately utilized to estimate the sequence of the target nucleic acids. In particular, an integrated semiconductor biosensor array device can be used to measure the addressable signals. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11447816-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11525156-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10174367-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11560588-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11485997-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11001881-B2 |
| priorityDate |
2015-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |