| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b94385f2fb1489adb0111d1b6f8351b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f02554d40f5ddd4677983b086736998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da1db2248df3a23e77fc7cfacc296b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cfc4580c1da22fa816a4f17b991d0c0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_201d8ac24582c90dfa9e03312ac3873b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 |
| filingDate |
2016-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0465248195b8b5e0a6e931dd51b301
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f00a05d69dd790ab2f57e3937d2e7914
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5a43ff9c508172fae5da57135c99584
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1092f42d23198a6a1053599bec1b56f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_583bcb9458607b54776e3b5a1be39d1a |
| publicationDate |
2018-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018016263-A1 |
| titleOfInvention |
Inhibitors of the renal outer medullary potassium channel |
| abstract |
The present invention provides compounds of Formula (I); and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention. |
| priorityDate |
2015-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |