| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e508108652064b8b02851ec467a0c142 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-1132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-1107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 |
| filingDate |
2016-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee1736d3677450d5fdae0721433c8804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e11ed127a44b6f8a3b1acc1f28dd7884
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ce06215744363eec9704c365f732907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4854494be83f3793461483b45516c8ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2e983cf471a7e7014f8ceb6de1cab60 |
| publicationDate |
2018-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018000983-A1 |
| titleOfInvention |
Hydrogels and use thereof in anastomosis procedures |
| abstract |
This disclosure provides novel hydrogels that can undergo multiple gel-sol transitions and methods of making and using such hydrogels, particularly in anastomosis procedures. The peptide hydrogels comprising a fibrillar network of peptides that are in an amphiphilic β-hairpin conformation. The peptides comprise photo-caged glutamate residues with a neutral photocage that can be photolytically selectively uncaged to disrupt the fibrillar network and trigger an irreversible gel-sol phase transition of the hydrogel. Isolated peptides for making the disclosed hydrogels are provided, as are methods of using the peptide hydrogels in anastomosis procedures. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11174288-B2 |
| priorityDate |
2015-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |