http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017360721-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_72046362a91a0f0277abe5495e47790f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 |
| filingDate | 2016-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4473abc90de06da25d3604b491bfe1c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52d59ae320e2fc5082eaab2e9b9d69f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0078e5113d9c46aaa26c7e592ba9982 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53c68fcf84ecf0727d6b0af2951e9723 |
| publicationDate | 2017-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2017360721-A1 |
| titleOfInvention | Hydroxynaphthoquinone compounds for treatment of non-small cell lung cancer |
| abstract | A compound suitable for treating EGFR-dependent non-small cell lung cancer exceptionally inhibits activity of the EGFR kinase, in particular in EGFR-dependent non-small cell lung cancer with intrinsic or acquired resistance against at least one EGFR inhibitor. Methods for inhibiting EGFR kinase activity in non-small cell lung cancer cells which harbor an abnormality in the EGFR gene and for targeting cancer cells harboring an abnormality in EGFR gene by contacting EGFR-dependent non-small cell lung cancer cells with said compound are also provided. The compounds allow for an advantageous inhibition of the EGFR kinase activity and induction of apoptosis of the non-small cell lung cancer cells with abnormality in the EGFR gene. Hence, said compounds represent a highly promising treatment option for patients harboring EGFR-dependent cancer. |
| priorityDate | 2016-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.