| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8dfbbbffb369b38b3910e80e1f5fbb63 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-395 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0618
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-545 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-545 |
| filingDate |
2015-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87f0e507918e5b21a0ebc46943c91e55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0bfbc9ef8ea9f4208fbbd9a954fc337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e7bec0f31da4b5bf4313b75abb5523e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fbf309cfa837094b261f6e44c617dfd |
| publicationDate |
2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017342380-A1 |
| titleOfInvention |
Improvements in Oligodendroglial Cell Culturing Methods and in Methods for Treating Neurodegenerative Disorders by Using Thyroid Hormones or Analogues |
| abstract |
The present invention relates to methods of treating or ameliorating certain neurodegenerative disorders (namely, dysmyelinating and demyelinating disorders) in patients in need of such treatment or amelioration. The invention provides methods of treating or ameliorating a patient in need of such treatment and includes the administration to the patient of: (a) thyroid hormones or thyroid hormone analogues; (b) cell replacement therapies involving the use of homogenous Oligodendrocyte Precursor Cells derived from embryonic stem cells that have been treated with thyroid hormones or thyroid hormone analogues; (c) gene therapy to correct mutated genes in vivo; or (d) a combination of two or more of (a), (b) and (c). The invention also provides compositions and formulations of thyroid hormones and thyroid hormone analogues for use in treating or ameliorating such disorders. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112513257-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114561355-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114540301-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023165062-A1 |
| priorityDate |
2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |