| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_674c74f15c753e23c6e1cfb415f9cc29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da6fff866a7b03daabef56aaf87f071a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate |
2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58f6beec5d5ec221fd15f4f9837c55f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87e239f8fa9275597b278e2096b490ee |
| publicationDate |
2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017342077-A1 |
| titleOfInvention |
Diazene directed modular synthesis of compounds with quaternary carbon centers |
| abstract |
Diazene-directed modular synthesis is described for the preparation Csp2-Csp3 and Csp3-Csp3 linkages where one or more stereogenic quaternary carbon centers are formed. The disclosed methods are directed to the preparation of compounds of Formula (I), or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, from compounds of Formula (II): n n n n n n n n n n wherein R 1 -R 5 and q are as defined independently for each occurrence herein. A wide variety of compounds can be accessed in this manner, including oligocyclotryptamines, where the stereochemistry of each subunit is beneficially secured before fragment coupling. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918627-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113880847-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10640508-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535634-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918735-B2 |
| priorityDate |
2016-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |