| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b36726b8c2d3a2fe627ab8caf1e052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60562001cc0ecc77b0a4a8e3c41670bd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3895
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3612
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-225
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3817 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 |
| filingDate |
2015-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fd5163cdeaeffd0761e6ba8f4530a71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abfb12afcec293025d54af0cabab7230 |
| publicationDate |
2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017306295-A1 |
| titleOfInvention |
Cartilage gel for cartilage repair, comprising chitosan and chondrocytes |
| abstract |
The present invention concerns a method for obtaining an implantable cartilage gel for tissue repair of hyaline cartilage, comprising particles of chitosan hydrogel and cells that are capable of forming hyaline cartilage, said method comprising a step for amplification of primary cells in a three-dimensional structure comprising particles of physical hydrogel of chitosan or a chitosan derivative, then a step for re-differentiation and induction of the synthesis of extracellular matrix by said amplified cells, in the same three-dimensional structure, wherein said cells are primary articular chondrocytes and/or mesenchymal stem cells differentiated into chondrocytes. The present invention also concerns the cartilage gel obtained thereby, and its various uses for cartilage repair following a traumatic lesion or an osteoarticular disease such as osteoarthritis. The invention also concerns a three-dimensional matrix comprising particles of physical hydrogel of chitosan or of chitosan derivative, optionally supplemented with an anionic molecule such as hyaluronic acid or a derivative of hyaluronic acid or a complex of hyaluronic acid. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11576927-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898608-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115154673-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019113511-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114652895-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11666239-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11745001-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022125177-A1 |
| priorityDate |
2014-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |