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publicationDate 2017-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2017253932-A1
titleOfInvention Method for detecting bcr-abl inhibitor resistance-related mutation and data acquisition method for predicting bcr-abl inhibitor resistance using the same
abstract An object of the present invention is to detect a mutation related to BCR-ABL inhibitor resistance with high accuracy for chronic myelogenous leukemia or the like. A method for detecting the mutation comprises the steps of: amplifying a region including a fusion site and a mutation site related to BCR-ABL inhibitor resistance contained in a BCR-ABL fusion gene using a biological sample collected from a subject; and genotyping of the mutation site related to BCR-ABL inhibitor resistance using nucleic acids amplified in the above step.
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