http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017224711-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc64a0225ee1b588c1d7af77250eee01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_490ded5d7eeddb213ebbff5532964313 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-688 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-688 |
filingDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_452a1bce4e1dea7d12524f0432163b3d |
publicationDate | 2017-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2017224711-A1 |
titleOfInvention | Compositions and methods for the treatment of neurodegenerative diseases |
abstract | In some embodiments, the present disclosure pertains to a composition for modulating the expression of at least one gene associated with neuronal cell survival or stability. In some embodiments, the present disclosure provides for compositions for the treatment of neurodegenerative diseases comprising one or more phosphate complexes of platinum of the formulas I, II, III and IV as set forth in FIG. 1. In some embodiments, the present disclosure relates to a method of treating a neurodegenerative disorder comprising administering therapeutically effective amounts of at least one of the aforementioned compositions described supra to a subject in need thereof, such that the compounds are effective in modulating the expression of a gene selected from the group consisting of NMDA-receptor, ATF, PPT2, HPD, EGR2, SLC7A11, FosB, SQSTM1, TMEM106B, RAB27A, STOX1, and SLC39A3. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111328330-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11439619-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019051246-A1 |
priorityDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 543.